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AI agent performs brain surgery on mouse using motorized rig

An Anthropic Sonnet-controlled motorized rig performed gene therapy brain surgery on a mouse to treat epilepsy, after Opus 5.5 refused the experiment and Opus 5 warned it might stop mid-operation.

Read the full story at Tom's Hardware ↗

Timeline · 2 reports

  1. 2026-10-31 12:00 · Tom's Hardware
    AI agent used to perform controversial brain surgery on a mouse, Anthropic Sonnet-controlled motorized surgery rig — Opus 5.5 refused to conduct biological experiment, Sonnet given free rein to treat epilepsy with a range of gene therapy vectors after
  2. 2026-10-31 12:00 · Tom's Hardware
    AI agent used to perform controversial brain surgery on a mouse, Anthropic Sonnet controlled motorized surgery rig

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