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CASP-DREAM TAP Challenge: TCR + peptide-MHC activation prediction with unseen test peptides [N]

A new contest for anyone training sequence models on TCRs. Given a TCR sequence and a peptide-HLA, predict whether the T cell activates. Inputs are amino acid sequences, the benchmark is about 5,800 labeled combinations, and every test peptide is at least four edits (Levenshtein distance) away from…

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  1. 2026-11-06 20:22 · r/MachineLearning
    CASP-DREAM TAP Challenge: TCR + peptide-MHC activation prediction with unseen test peptides [N]

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