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How to Connect Python to the Ethereum Sepolia Testnet Using Web3.py

This story is from 2026-10-23. It is preserved in the archive; the latest stories are on the live feed.

Connecting Python applications to smart contracts allows you to build tamper-proof logging pipelines. Here is a quick, step-by-step guide to sending data to the Sepolia testnet using Web3.py. Prerequisites Python 3.8+ installed An RPC URL (from Infura or Alchemy) A Sepolia testnet wallet address &…

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  1. 2026-10-23 13:39 · DEV Community — AI
    How to Connect Python to the Ethereum Sepolia Testnet Using Web3.py

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