Inference-Time Projection for Physically Valid Biomolecular Diffusion Models
arXiv:2610.07037v1 Announce Type: new Abstract: AlphaFold 3-style cofolding models predict biomolecular complexes with high structural accuracy, yet a large fraction of their outputs are physically invalid: chains overlap at interfaces, ligand bond lengths and angles are distorted, rings are non-pl…
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- 2026-10-07 04:00 · arXiv cs.AI
Inference-Time Projection for Physically Valid Biomolecular Diffusion Models