Protein language models: an embedding is not a mutation-effect score
Suppose you want to choose which changes to an enzyme to test in the lab. A protein language model can help rank candidates, but extracting an embedding does not by itself give you a prediction of enzyme activity. An embedding is a vector of numbers representing the sequence. ESM can return one vec…
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- 2026-10-14 13:34 · r/ArtificialInteligence
Protein language models: an embedding is not a mutation-effect score