Reverse Item Response Theory for Sparsity-Robust Ranking in Fragmented Cancer Drug-Response Matrices
arXiv:2610.00002v1 Announce Type: new Abstract: We introduce reverse Item Response Theory (IRT) to pharmacogenomic drug-response analysis by treating cancer types as latent "subjects" with resistance ability and drugs as "items" with evasion difficulty. Applied to 242,036 drug sensitivity measureme…
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- 2026-10-02 04:00 · arXiv cs.LG
Reverse Item Response Theory for Sparsity-Robust Ranking in Fragmented Cancer Drug-Response Matrices